Difference: ProteinNmrCourseSyllabus2014 ( vs. 1)

Syllabus

January 29        Organizational Meeting                                                         Ronnie Ghose

February 5        Introduction to modern NMR – the basics                                                     Mike Goger
           Features of NMR Spectra: Classical Representation of the NMR Experiment          Mike Goger

February 12    No classes – Lincoln’s birthday

February 19    Semi-classical approach to FT NMR – the Master Equation                        Ronnie Ghose
           Introduction to product operators                                              Ronnie Ghose

February 26    Application of product operators                                              Ronnie Ghose
           Multi-dimensional NMR                                                         Ronnie Ghose

March 5        Protein NMR Spectroscopy - the HSQC experiment and variants                     Shibani Bhattacharya
           Triple-resonance Experiments and Assignment of Backbone Resonances – I       Shibani Bhattacharya

March 12        Triple-resonance Experiments and Assignment of Backbone Resonances – II      Shibani Bhattacharya
           Review of triple-resonance experiments and introduction to assignments           Shibani Bhattacharya/Kaushik Dutta

March 19*     Use of NMRView for resonance assignment                                           Kaushik Dutta/Bruce Johnson

March 26       Review of assignment procedures                                              Kaushik Dutta
          Generation of structural constraints                                              Ronnie Ghose

April 2*       Structure calculations using XPLOR-NIH                                      Charles Schwieters
          Take-home midterm

April 9       No class – Spring break

April 16      Review of structure calculations                                                      Kaushik Dutta
          Accuracy and precision of NMR structures                                           Ronnie Ghose

April 23       No class – ENC

April 30       Isotope labeling strategies for NMR - I                                      Kevin Gardner/Fernando Correa
          Isotope labeling strategies for NMR - II                                      Kevin Gardner/Fernando Correa

May 7       NMR relaxation and dynamics – I                                              Art Palmer
          NMR relaxation and dynamics – II                                              Art Palmer

May 14       Using chemical shifts for structure determination                           Paul Robustelli
          IDPs                                                                       TBA

May 21          Final presentations


*To be held in the ASRC auditorium from 10 AM – 4 PM.


   * Set ALLOWTOPICVIEW = 

-- Main.MichaelGoger - 15 Jan 2015