Difference: BtrrInfo (1 vs. 42)

Revision 4210 Aug 2010 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Main.ArthurPalmer -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques
    2. PRE
    3. solid state
Changed:
<
<

Driving Biomedical Projects (DBP) Main.LetterDraftDBP?

>
>

Driving Biomedical Projects (DBP) LetterDraftDBP

 
  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Main.NmrEducation )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
  6. Consultants invited (or pending) DraftBtrrConsultantLetter
    1. Numerical methods Main.AmitSinger
    2. Database and record keeping Main.ZsoltZolnai
    3. NMR data handling Main.BruceJohnson
    4. Protein expression methods Main.JamesLove Main.StevenAlmo
    5. Crystallography Main.WayneHendrickson

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

META TOPICMOVED by="DavidCowburn" date="1277230357" from="Main.BtrrInfo" to="Staffarchive.BtrrInfo"

Revision 4122 Jun 2010 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Main.ArthurPalmer -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP) Main.LetterDraftDBP?

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Main.NmrEducation )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
Changed:
<
<
  1. Consultants invited (or pending) Main.DraftBtrrConsultantLetter?
>
>
  1. Consultants invited (or pending) DraftBtrrConsultantLetter
 
    1. Numerical methods Main.AmitSinger
    2. Database and record keeping Main.ZsoltZolnai
    3. NMR data handling Main.BruceJohnson
    4. Protein expression methods Main.JamesLove Main.StevenAlmo
    5. Crystallography Main.WayneHendrickson

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

META TOPICMOVED by="DavidCowburn" date="1277230357" from="Main.BtrrInfo" to="Staffarchive.BtrrInfo"

Revision 4022 Jun 2010 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics
Changed:
<
<		PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.
>
>		PI Main.ArthurPalmer -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.
 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
Changed:
<
<
    1. shuttle probe techniques?
>
>
    1. shuttle probe techniques
 
    1. PRE
    2. solid state
Changed:
<
<

Driving Biomedical Projects (DBP) LetterDraftDBP

>
>

Driving Biomedical Projects (DBP) Main.LetterDraftDBP?

 
  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
Changed:
<
<
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
  • David Fushman?
>
>
 

Training

Changed:
<
<
  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )
>
>
  1. Access of NIH PI's to related NYSBC courses on line. (See Main.NmrEducation )
 

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
Changed:
<
<
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  1. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Crystallography Wayne Hendrickson?
>
>
  1. Consultants invited (or pending) Main.DraftBtrrConsultantLetter?
    1. Numerical methods Main.AmitSinger
    2. Database and record keeping Main.ZsoltZolnai
    3. NMR data handling Main.BruceJohnson
    4. Protein expression methods Main.JamesLove Main.StevenAlmo
    5. Crystallography Main.WayneHendrickson
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Added:
>
>
META TOPICMOVED by="DavidCowburn" date="1277230357" from="Main.BtrrInfo" to="Staffarchive.BtrrInfo"
 

Revision 3903 Dec 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP) LetterDraftDBP

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
  • David Fushman?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3824 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP) LetterDraftDBP

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
  • David Fushman?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3721 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state
Changed:
<
<

Driving Biomedical Projects (DBP)

>
>

Driving Biomedical Projects (DBP) LetterDraftDBP

 
  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
  • David Fushman?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3620 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Integrin signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
  • David Fushman?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3519 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Biomedical Technology Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
Changed:
<
<
  1. Epigenetic related signaling
>
>
  1. Integrin signaling
 

Collaboration and Service

Changed:
<
<		The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas
>
>		The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas . Draft Letter for Collaborators
 
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
Added:
>
>
  • David Fushman?
 

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
Deleted:
<
<
    1. Small angle scattering Zimei Bu?
 
    1. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3418 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Changed:
<
<		Research Resource in Macromolecular Dynamics
>
>		Biomedical Technology Research Resource in Macromolecular Dynamics
 PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Small angle scattering Zimei Bu?
    6. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3314 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
Changed:
<
<
    1. Database and record keeping Zsolt Zolnai?
>
>
    1. Database and record keeping Zsolt Zolnai?
 
    1. NMR data handling Bruce Johnson?
    2. Protein expression methods James Love? Steven Almo?
    3. Small angle scattering Zimei Bu?
    4. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3214 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics
Added:
>
>		PI Arthur Palmer? -- please e-cc dcadmin@nysbc.org on matters concerning this proposal.
 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Small angle scattering Zimei Bu?
    6. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3114 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Added:
>
>		The following are involved in likely collaborations with the BTRR, including topics in the "Driving Biomedical Projects" areas
 
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Small angle scattering Zimei Bu?
    6. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 3014 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Added:
>
>
  • Aneel Aggarwal?
  • David Cowburn?
  • Mark Girvin?
  • Steve Hubbard?
  • Ann McDermott?
  • Moosa Mohammadi?
 

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. NMR data handling Bruce Johnson?
    4. Protein expression methods James Love? Steven Almo?
    5. Small angle scattering Zimei Bu?
    6. Crystallography Wayne Hendrickson?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2914 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Added:
>
>
 

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
Changed:
<
<
  1. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
>
>
  1. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
 
    1. Database and record keeping Zsolt Zolnai?
Changed:
<
<
    1. Protein expression methods James Love? Steven Almo?
>
>
    1. NMR data handling Bruce Johnson?
Added:
>
>
    1. Protein expression methods James Love? Steven Almo?
 
    1. Small angle scattering Zimei Bu?
Changed:
<
<
    1. Crystallography Wayne Hendrickson?
>
>
    1. Crystallography Wayne Hendrickson?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2814 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

An early draft proposal (5 pages) is available.?

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?
Added:
>
>
    1. Crystallography Wayne Hendrickson?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2714 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.
Changed:
<
<		An early draft proposal (5 pages) is available.?
>
>		An early draft proposal (5 pages) is available.?
 

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2614 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Research Resource in Macromolecular Dynamics

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.
Added:
>
>		An early draft proposal (5 pages) is available.?
 

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2514 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

Added:
>
>		Research Resource in Macromolecular Dynamics
 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
    3. solid state

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2414 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs, including PRE tags
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?
    2. PRE
Added:
>
>
    1. solid state
 

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2314 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
Changed:
<
<
    1. chemical biology approaches and non-natural analogs
>
>
    1. chemical biology approaches and non-natural analogs, including PRE tags
 
  1. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  2. NMR technology areas
    1. shuttle probe techniques?
Added:
>
>
    1. PRE
 

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Signal transduction
    1. Kinases/ phophatases
    2. ectodomain signaling
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2214 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
Changed:
<
<
  1. Kinases/ phophatases
>
>
  1. Signal transduction
Added:
>
>
    1. Kinases/ phophatases
    2. ectodomain signaling
 
  1. Components of the dynamic interactome
  2. Pleomorphism of nucleic acids
  3. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2114 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending) Draft Btrr Consultant Letter
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 2013 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
Changed:
<
<
  1. Consultants invited (or pending)
>
>
  1. Consultants invited (or pending) Draft Btrr Consultant Letter
 
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
    4. Small angle scattering Zimei Bu?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1913 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending)
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
Changed:
<
<
    1. Small angle scattering Ziemei Bu?
>
>
    1. Small angle scattering Zimei Bu?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1813 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited (or pending)
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
    3. Protein expression methods James Love? Steven Almo?
Changed:
<
<
    1. Small angle scattering Zemei Bu?
>
>
    1. Small angle scattering Ziemei Bu?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1713 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
Changed:
<
<
  1. Consultants invited
>
>
  1. Consultants invited (or pending)
 
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zsolt Zolnai?
Added:
>
>
    1. Protein expression methods James Love? Steven Almo?
    2. Small angle scattering Zemei Bu?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1613 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
  6. Consultants invited
    1. Numerical methods Amit Singer?
Changed:
<
<
    1. Database and record keeping Zolt Zolnai?
>
>
    1. Database and record keeping Zsolt Zolnai?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1513 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Added:
>
>
  1. Access of NIH PI's to related NYSBC courses on line. (See Nmr Education? )
 

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
    • TBA
  5. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
Added:
>
>
  1. Consultants invited
    1. Numerical methods Amit Singer?
    2. Database and record keeping Zolt Zolnai?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1412 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
Added:
>
>
    • TBA
 
  1. Local Executive Committee
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1312 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee
Added:
>
>
    • Chair - TBA, Arthur Palmer? PI, Mark Girvin?, David Eliezer?, David Cowburn?
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1212 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics simulation
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1112 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
Changed:
<
<
  1. Analysis of NMR data for dynamic processes including molecular dynamics
>
>
  1. Analysis of NMR data for dynamic processes including molecular dynamics simulation
 
  1. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 1012 Nov 2008 - Main.DavidCowburn

 Contents

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee
Changed:
<
<
>
>
 
  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 912 Nov 2008 - Main.DavidCowburn

 Contents
Changed:
<
<

DRAFT IN PROGRESS %D% Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

>
>

DRAFT IN PROGRESS Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 812 Nov 2008 - Main.DavidCowburn

 Contents
Changed:
<
<

DRAFT IN PROGRESS %W% Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

>
>

DRAFT IN PROGRESS %D% Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 712 Nov 2008 - Main.DavidCowburn

 Contents
Changed:
<
<

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

>
>

DRAFT IN PROGRESS %W% Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

 

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques?

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 612 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
Changed:
<
<
    1. shuttle probe techniques
>
>
    1. shuttle probe techniques?
 

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
  6. Pleomorphism of nucleic acids
  7. Epigenetic related signaling

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 512 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome
Added:
>
>
  1. Pleomorphism of nucleic acids
  2. Epigenetic related signaling
 

Collaboration and Service

Training

Dissemination

Administration

  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 412 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques

Driving Biomedical Projects (DBP)

  1. Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinases/ phophatases
  5. Components of the dynamic interactome

Collaboration and Service

Training

Dissemination

Administration

Changed:
<
<

Organizational structure

Staff responsibilities

Resource operating procedure

External Advisory Committee

Local Executive Committee

>
>
  1. Organizational structure
  2. Staff responsibilities
  3. Resource operating procedure
  4. External Advisory Committee
  5. Local Executive Committee
 

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 312 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques

Driving Biomedical Projects (DBP)

Changed:
<
<
  1. . Intrinsically unstructured proteins
>
>
  1. Intrinsically unstructured proteins
 
  1. General mechanisms in enzymology
  2. Membrane proteins
Changed:
<
<
  1. Kinase/ phophatases
>
>
  1. Kinases/ phophatases
 
  1. Components of the dynamic interactome

Collaboration and Service

Training

Dissemination

Administration

Organizational structure

Staff responsibilities

Resource operating procedure

External Advisory Committee

Local Executive Committee

Changed:
<
<

subsub level topic

>
>
 
  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 212 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.
Added:
>
>

Components

Technology Research and Development

Infrastructure

  1. Measurement of intermediate time scale motions
  2. Measurement of fast time scale motions
  3. Provision of protein constructs with appropriate isotopic labeling
    1. Segmental labeling
    2. cell free labeling
    3. chemical biology approaches and non-natural analogs
  4. Analysis of NMR data for dynamic processes including molecular dynamics
  5. NMR technology areas
    1. shuttle probe techniques

Driving Biomedical Projects (DBP)

  1. . Intrinsically unstructured proteins
  2. General mechanisms in enzymology
  3. Membrane proteins
  4. Kinase/ phophatases
  5. Components of the dynamic interactome

Collaboration and Service

Training

Dissemination

Administration

Organizational structure

Staff responsibilities

Resource operating procedure

External Advisory Committee

Local Executive Committee

 

subsub level topic

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

Revision 111 Nov 2008 - Main.DavidCowburn

 Contents

Public information concerning application from NYSBC to NIH-NCRR-BTRR program for Dec 2 deadline, 2008

NIH references

Resume

NYSBC has a unique infrastructure and intellectual focus group related to studying dynamic processes of biomolecules, principally by NMR.

subsub level topic

  • Set ALLOWTOPICVIEW =

-- DavidCowburn - 11 Nov 2008

View topic  |  History: r42 < r41 < r40 < r39  |  More topic actions...
 
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