Difference: LetterDraftDBP (1 vs. 5)
Revision 510 Aug 2010 - Main.DavidCowburn
| Changed: | ||||||||
| < < |
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org | |||||||
| > > |
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org | |||||||
| (ecopy to dcadmin@nysbc.org )
YOUR LETTERHEAD
Professor Arthur G. Palmer III NYSBC 89 Convent Avenue NY NY 10027 Dear Art: Your proposal to the NIH-NCRR-BTRR Program for a Center for Macromolecular Dynamics Please edit the following in your own style and add your expertise area as you see it.... I am pleased to support in your proposal for a Biomedical Technology Research Resource in Macromolecular Dynamics from the National Center for Research Resources (NCRR). Please edit in your own style your area of interest (two examples) [Protein conformational dynamics and kinetic transitions between conformational states are central aspects of protein folding and misfolding, and hence of human health and disease. ] [RNA is an inherently dynamic molecule and recent results from my own and other laboratories indicates that proper understanding of function requires structural and dynamical studies in large, biologically relevant constructs.] Please comment about the need for new technological developments related to your area. as an example... The area of selective diffusion through the nuclear pore complex is now well understood in terms of likely components, but the macroscopic, meso- and molecular scale interactions are needed and new approaches to this problem require development because of the size and complexity of the systems involved. We anticipate that the molecular details of the involved interactions will provide an important step in understanding molecular machines at the surface of the cell in general, and provide an important example of how nanoscale biological interactions arise from molecular details. Please comment on the generic biomedical foci, as an example ... Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... Sincerely, YOUR_NAME Please also send you NIH biosketch to dcadmin@nysbc.org Please edit in your own style something about your experience generally related to the proposal My experience includes BLOW YOUR OWN HORN related to this proposal. My current biographical sketch is attached Sincerely, MYNAME As related to above, list of RELATED publications, please limit the total length to one page | ||||||||
| Added: | ||||||||
| > > |
| |||||||
Revision 422 Jun 2010 - Main.DavidCowburn
| Changed: | ||||||||
| < < |
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org | |||||||
| > > |
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org | |||||||
| (ecopy to dcadmin@nysbc.org )
YOUR LETTERHEAD
Professor Arthur G. Palmer III NYSBC 89 Convent Avenue NY NY 10027 Dear Art: Your proposal to the NIH-NCRR-BTRR Program for a Center for Macromolecular Dynamics Please edit the following in your own style and add your expertise area as you see it.... I am pleased to support in your proposal for a Biomedical Technology Research Resource in Macromolecular Dynamics from the National Center for Research Resources (NCRR). Please edit in your own style your area of interest (two examples) [Protein conformational dynamics and kinetic transitions between conformational states are central aspects of protein folding and misfolding, and hence of human health and disease. ] [RNA is an inherently dynamic molecule and recent results from my own and other laboratories indicates that proper understanding of function requires structural and dynamical studies in large, biologically relevant constructs.] Please comment about the need for new technological developments related to your area. as an example... The area of selective diffusion through the nuclear pore complex is now well understood in terms of likely components, but the macroscopic, meso- and molecular scale interactions are needed and new approaches to this problem require development because of the size and complexity of the systems involved. We anticipate that the molecular details of the involved interactions will provide an important step in understanding molecular machines at the surface of the cell in general, and provide an important example of how nanoscale biological interactions arise from molecular details. Please comment on the generic biomedical foci, as an example ... Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... Sincerely, YOUR_NAME Please also send you NIH biosketch to dcadmin@nysbc.org Please edit in your own style something about your experience generally related to the proposal My experience includes BLOW YOUR OWN HORN related to this proposal. My current biographical sketch is attached Sincerely, MYNAME As related to above, list of RELATED publications, please limit the total length to one page | ||||||||
Revision 321 Nov 2008 - Main.DavidCowburn
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org (ecopy to dcadmin@nysbc.org ) YOUR LETTERHEAD Professor Arthur G. Palmer III NYSBC 89 Convent Avenue NY NY 10027 Dear Art: Your proposal to the NIH-NCRR-BTRR Program for a Center for Macromolecular Dynamics Please edit the following in your own style and add your expertise area as you see it.... I am pleased to support in your proposal for a Biomedical Technology Research Resource in Macromolecular Dynamics from the National Center for Research Resources (NCRR). Please edit in your own style your area of interest (two examples) [Protein conformational dynamics and kinetic transitions between conformational states are central aspects of protein folding and misfolding, and hence of human health and disease. ] [RNA is an inherently dynamic molecule and recent results from my own and other laboratories indicates that proper understanding of function requires structural and dynamical studies in large, biologically relevant constructs.] Please comment about the need for new technological developments related to your area. as an example... The area of selective diffusion through the nuclear pore complex is now well understood in terms of likely components, but the macroscopic, meso- and molecular scale interactions are needed and new approaches to this problem require development because of the size and complexity of the systems involved. We anticipate that the molecular details of the involved interactions will provide an important step in understanding molecular machines at the surface of the cell in general, and provide an important example of how nanoscale biological interactions arise from molecular details. Please comment on the generic biomedical foci, as an example ... | ||||||||
| Changed: | ||||||||
| < < | Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control2 may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. | |||||||
| > > | Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. | |||||||
| If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... Sincerely, YOUR_NAME Please also send you NIH biosketch to dcadmin@nysbc.org Please edit in your own style something about your experience generally related to the proposal My experience includes BLOW YOUR OWN HORN related to this proposal. My current biographical sketch is attached Sincerely, MYNAME As related to above, list of RELATED publications, please limit the total length to one page | ||||||||
Revision 221 Nov 2008 - Main.DavidCowburn
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org (ecopy to dcadmin@nysbc.org ) YOUR LETTERHEAD Professor Arthur G. Palmer III NYSBC 89 Convent Avenue NY NY 10027 Dear Art: Your proposal to the NIH-NCRR-BTRR Program for a Center for Macromolecular Dynamics Please edit the following in your own style and add your expertise area as you see it.... I am pleased to support in your proposal for a Biomedical Technology Research Resource in Macromolecular Dynamics from the National Center for Research Resources (NCRR). Please edit in your own style your area of interest (two examples) [Protein conformational dynamics and kinetic transitions between conformational states are central aspects of protein folding and misfolding, and hence of human health and disease. ] [RNA is an inherently dynamic molecule and recent results from my own and other laboratories indicates that proper understanding of function requires structural and dynamical studies in large, biologically relevant constructs.] Please comment about the need for new technological developments related to your area. as an example... The area of selective diffusion through the nuclear pore complex is now well understood in terms of likely components, but the macroscopic, meso- and molecular scale interactions are needed and new approaches to this problem require development because of the size and complexity of the systems involved. We anticipate that the molecular details of the involved interactions will provide an important step in understanding molecular machines at the surface of the cell in general, and provide an important example of how nanoscale biological interactions arise from molecular details. Please comment on the generic biomedical foci, as an example ... Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control2 may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. | ||||||||
| Changed: | ||||||||
| < < | _If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... | |||||||
| > > | If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... | |||||||
| Sincerely,
YOUR_NAME
Please also send you NIH biosketch to dcadmin@nysbc.org Please edit in your own style something about your experience generally related to the proposal My experience includes BLOW YOUR OWN HORN related to this proposal. My current biographical sketch is attached Sincerely, MYNAME As related to above, list of RELATED publications, please limit the total length to one page | ||||||||
Revision 121 Nov 2008 - Main.DavidCowburn
Confidentiality : we will try to make anything you provide as confidential as anything usually included in any proposal to NIH. However, a significant number of coordinators are likely to have access to your materials, and so you are advised to provide nothing of a pre-publication nature which would be of material disadvantage to you if publicly available. Biosketch Please include a standard NIH biosketch including your current/recent support information. Inquires Dont hesitate to email us at dcadmin@nysbc.org with any issues. The PI can be contacted at agp6@columbia.edu SEND LETTER BY EMAIL TO dcadmin@nysbc.org . If you absolutely insist on fax, then please fax to +12122082597, and advise us of the fax at dcadmin@nysbc.org (ecopy to dcadmin@nysbc.org ) YOUR LETTERHEAD Professor Arthur G. Palmer III NYSBC 89 Convent Avenue NY NY 10027 Dear Art: Your proposal to the NIH-NCRR-BTRR Program for a Center for Macromolecular Dynamics Please edit the following in your own style and add your expertise area as you see it.... I am pleased to support in your proposal for a Biomedical Technology Research Resource in Macromolecular Dynamics from the National Center for Research Resources (NCRR). Please edit in your own style your area of interest (two examples) [Protein conformational dynamics and kinetic transitions between conformational states are central aspects of protein folding and misfolding, and hence of human health and disease. ] [RNA is an inherently dynamic molecule and recent results from my own and other laboratories indicates that proper understanding of function requires structural and dynamical studies in large, biologically relevant constructs.] Please comment about the need for new technological developments related to your area. as an example... The area of selective diffusion through the nuclear pore complex is now well understood in terms of likely components, but the macroscopic, meso- and molecular scale interactions are needed and new approaches to this problem require development because of the size and complexity of the systems involved. We anticipate that the molecular details of the involved interactions will provide an important step in understanding molecular machines at the surface of the cell in general, and provide an important example of how nanoscale biological interactions arise from molecular details. Please comment on the generic biomedical foci, as an example ... Development of the model systems is likely to have significant biotechnological impact for purification of large complexes, e.g. for protein therapeutics, and for new devices for diagnostics where specificity may be built into the cargo selection or the filter elements to provide molecular detection of large complexes at high sensitivity on microsamples without recourse to multiple steps in, for example, immunoassays. Over a longer term, the role of physiological regulation of the NPC in transcriptional control2 may be illustrated by extending these studies from the model system. Additionally, gene therapy may be advanced by identification of enhanced methods for nuclear transport. _If you have had previous collaborations with Art, please comment, e.g. In our previous collaborative work, your development of procedures for ... was critical for the success of our analysis of ... Sincerely, YOUR_NAME Please also send you NIH biosketch to dcadmin@nysbc.org Please edit in your own style something about your experience generally related to the proposal My experience includes BLOW YOUR OWN HORN related to this proposal. My current biographical sketch is attached Sincerely, MYNAME As related to above, list of RELATED publications, please limit the total length to one page |
View topic
| History: r5 < r4 < r3 < r2
| More topic actions...
Copyright © by the contributing authors. All material on this collaboration platform is the property of the contributing authors.
Ideas, requests, problems regarding this intranet, Send feedback
Ideas, requests, problems regarding this intranet, Send feedback